"Potentially, our work could offer something to help people suffering from a variety of problems".
In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss, The Manc reports.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they're the only organ in humans that regenerates automatically and regularly, even if they haven't been injured - and it's from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles - including stem cells - divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: "In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
Scientists have discovered a potential cure for baldness thanks to new research / Credit: Tengyart (via Unsplash)
"In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing."
"TGF-beta has two opposite roles," Wang added.
"It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death."
While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it's a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it's the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: "Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle."
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Of course, there's still some way to go until baldness is cured - however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
"Potentially, our work could offer something to help people suffering from a variety of problems," Wang concluded.
There's a brand-new Catalonian-inspired café and bar venue coming to Sheffield where you can grab a coffee or a pint at the same time.
This is Cats, a combined café and bar space that's making its way to Broomhill and offering anyone visiting the chance to experience a taste of Spain without having to fork out the cost of a plane ticket.
Catalonia is famous for many notable like impressive architecture such as La Sagrada Familia, legendary performers like Rosalía and phenomenal all-day hospitality which this new site is hoping to emulate.
Although we might not be able to judge their skills as vocalists, when it comes to construction and deconstruction they're excelling, as can be seen in their renovation progress documented across their socials.
Taking shape in the former Nibbles Pizza site on Ashdell Road, although you might not be able to order a 12 inch meat feast anymore, Cats will be offering a range of interesting wines, beers and bar snacks.
In newly-released rendered images, a fitting wine-red colour has been used throughout both interior and exterior, the latter having a small seating adjacent to the front door.
Inside, you'll find lightbulbs dotted around the almost-180 degree-spanning window seating with small warm lights to set the mood.
Directly opposite will be the bar with a muted-concrete countertop that has a coffee machine on one end and draught beers on the other - the ultimate dream.
There's even a cellar area downstairs with banquette seating and those familiar tabletop lamps which help keep the atmosphere as relaxed and intimate as intended.
As the name may suggest, this place isn't exclusively for feline lovers as this Sheffield venue is promising to be a dog-friendly site stocking 'Cats' branded dog treats and water bowls.
Of course, this won't be exactly how this café and bar space will end up looking like as working with an older may pose some potential challenges, but these plans shouldn't differ too much.
We can't wait to get our claws on a glass of vino.
Featured Images - Cats Sheffield via Instagram (Supplied)
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Trains from Leeds ‘extremely limited’ amid record-breaking heatwave
Daisy Jackson
‘Extremely limited’ train services are running across Yorkshire this week as the country melts in a record-breaking heatwave.
Northern has reached out to passengers to warn that a ‘significantly reduced’ number of trains are operating in and out of Leeds.
They’re urging people to avoid travelling at all unless your journey is ‘absolutely essential’.
And if you do have to travel, they’ve warned of ‘significantly longer waiting times, busy trains and short-notice cancellations’.
The disruption is set to continue all day today and into tomorrow, Friday 26 June, as temperatures up north are forecast to hit 34ºC and an Amber weather warning for extreme heat covers much of the country.
Northern has assured passengers that they ‘are doing everything we can to keep people moving as efficiently as possible’.
Passengers are encouraged to check their journey before setting off, carry water, and avoid peak times where possible.
If you chose not to take a planned journey, you can claim a full refund on your ticket, or travel on another day using Northern’s ticket easement.
You can see the full travel advice for Northern HERE.
Northern said in a notice to passengers: “Due to the continued extreme heat, we have significantly reduced the number of trains running on routes in and out of Manchester, and services remain in high demand. This will now continue into Friday, 26 June.
“We strongly recommend customers consider whether their journey is necessary and if customers do choose to travel this week, they are advised to prepare for significantly longer waiting times, busy trains and short-notice cancellations.
“We would ask all customers to only travel if your journey is absolutely essential and to check your full journey before setting off.”
The Hoot -
27th July 2022 
