"Potentially, our work could offer something to help people suffering from a variety of problems".
In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss, The Manc reports.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they're the only organ in humans that regenerates automatically and regularly, even if they haven't been injured - and it's from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles - including stem cells - divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: "In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
Scientists have discovered a potential cure for baldness thanks to new research / Credit: Tengyart (via Unsplash)
"In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing."
"TGF-beta has two opposite roles," Wang added.
"It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death."
While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it's a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it's the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: "Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle."
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Of course, there's still some way to go until baldness is cured - however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
"Potentially, our work could offer something to help people suffering from a variety of problems," Wang concluded.
A £1.6m grant has been given by the government to Leeds City Council to help tackle rough sleeping.
The funding has been allocated to Leeds City Council as part of the Government’s national Rough Sleeping Programme.
The overall target is to help rough sleepovers off the streets by Christmas through providing safe accommodation.
The council have said that voluntary organisations and charities will be able to help them reach this target.
The council report said: "This funding will be used for immediate interventions to ensure all those rough sleeping have an offer of accommodation by Christmas and support longer term sustainment of accommodation.
“The initial target is to provide a suitable offer of accommodation for everyone who is rough sleeping by Christmas 2026.
“Providing a path into supported accommodation and independent living is the key objective and sustaining this independent living with, where necessary, ongoing support to prevent any return to rough sleeping and homelessness.”
The government announcement spoke of the scheme: "The programme is intended to support people experiencing rough sleeping.
"People experiencing rough sleeping may have differing entitlements to housing and support depending on their individual circumstances, including their immigration status and eligibility for public funds."
The funding is intended to help provide immediate support for people currently sleeping on the streets, while also helping them access longer-term accommodation and the support needed to maintain independent living.
By working with local charities and voluntary organisations, the council hopes to ensure people are not only offered a place to stay but are also given the help they need to avoid returning to the streets.
M&S launches massive recruitment drive in Leeds with hundreds of jobs available
Emily Sergeant
M&S has launched a massive recruitment drive across Yorkshire.
With the festive season fast approaching, and most British stores having already unveiled their Christmas ranges for 2026, one of the country’s largest brands has launched a massive UK-wide seasonal recruitment drives to gear up for what is always one of the busiest times of the year for the retail industry.
M&S has announced it will recruit for plenty of new colleagues across the UK.
As mentioned Christmas is one of the busiest moments of the year for M&S, and seasonal colleagues play a ‘vital’ part in delivering that.
Image: Supplied
New recruits will be tasked with helping M&S deliver a ‘brilliant’ service for customers.
Stores with vacancies span the whole of Leeds - including city centre, Moortown, Crown Point, White Rose Shopping Centre and Pudsey.
M&S says the roles are ‘fast-moving and hands-on’, with colleagues required to work together to make sure customers still get the very best of M&S, even at its busiest.
The roles will pay £13.41 per hour, with successful applicants receiving the training, tools and support needed to get up to speed quickly.
“We can’t wait to welcome over 300 new colleagues to our store teams here in Greater Manchester,” commented Zeba Khan, who is the Regional Manager at M&S.
“As we get ready for our busiest time of year, it’s a great opportunity to join us and help bring a magical M&S Christmas to our customers.
“We have a range of opportunities available, whether joining our city centre flagship or our fresh market-style foodhalls. We’re looking for colleagues who are passionate about delivering great customer service and being part of a team.”
Fancy it then? Applications are now open, and you can find out more and apply on the M&S Christmas careers page here.
The Hoot -
27th July 2022 
