"Potentially, our work could offer something to help people suffering from a variety of problems".
In what is a major breakthrough thanks to new research, scientists are claiming they have found a potential cure for hair loss, The Manc reports.
With statistics and estimations showing that approximately 85% of men and 40% of women will be affected by hair loss at some point in their lives, researchers at the University of California Riverside have been studying hair follicles in depth to try and find out as much as possible.
In a new study published in the Biophysical Journal, the team at UC Riverside explained that they decided to focus on hair follicles as they're the only organ in humans that regenerates automatically and regularly, even if they haven't been injured - and it's from this research that they they discovered that just a single chemical is the key cause for hair follicle cells dividing and dying.
They discovered a type of protein named TGF-beta.
TGF-beta controls the process in which cells in hair follicles - including stem cells - divide and form new cells, or orchestrate their own death, which eventually leads to the death of the whole hair follicle.
But could this be reversed and successfully cure baldness and heal wounds? Scientists hope so.
Explaining more about the discovery in the study, UC Riverside mathematical biologist and study co-author Qixuan Wang said: "In science fiction when characters heal quickly from injuries, the idea is that stem cells allowed it.
Scientists have discovered a potential cure for baldness thanks to new research / Credit: Tengyart (via Unsplash)
"In real life, our new research gets us closer to understanding stem cell behaviour, so that we can control it and promote wound healing."
"TGF-beta has two opposite roles," Wang added.
"It helps activate some hair follicle cells to produce new life, and later, it helps orchestrate apoptosis, the process of cell death."
While no one is entirely sure why follicles kill themselves, and some hypotheses suggest it's a trait inherited from animals shedding fur to survive hot summer temperatures, or trying to camouflage, what we do know is that with TGF-beta, as is the same with many chemicals, it's the amount that makes the difference, and if the cell produces a certain quantity of TGF-beta, then it activates cell division.
Wang continued: "Even when a hair follicle kills itself, it never kills its stem cell reservoir [as] when the surviving stem cells receive the signal to regenerate, they divide, make new cell and develop into a new follicle."
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Of course, there's still some way to go until baldness is cured - however, researchers have suggested that it may be possible to activate follicle stem cells and stimulate hair growth if more research is carried out on how TGF-beta communicates with other genes and promotes cell division.
If they can find a way to accurately control levels of the protein, then it could lead to an effective treatment for hair loss.
"Potentially, our work could offer something to help people suffering from a variety of problems," Wang concluded.
Ryanair is being investigated by the Government’s leading regulator over charging parents to sit with their children.
Currently, Ryanair ’s terms and conditions require at least one parent to sit with their children aged two-11 when they fly, but this is done through what the airline calls a ‘mandatory family seat’, meaning the parent must pay in order for them to secure a seat next to their child.
This fee applies to both outbound and return flights, and typically costs around £8 each way – but for all other passengers, reserving a seat is optional.
And it’s this that the Competition and Markets Authority (CMA) has launched an investigation .
Ryanair is being investigated over charging parents to sit with their children / Credit: Gerrie van der Walt (via Unsplash)
CMA evidence suggests this approach to seating is used across the majority of Ryanair’s UK routes, and the watchdog understands that Ryanair is the only major airline flying out of the UK to impose this charge.
Other airlines offer to seat children with a parent or guardian without the need for a paid-for adult seat reservation, or they allocate seats together automatically during booking for free.
The CMA says it’s investigating, in particular, whether Ryanair’s approach to seat reservations may mean parents are being charged for the airline to meet its child safety and disability‑related obligations as set out under aviation rules.
The watchdog wants to determine whether or not this practice is in line with consumer law, and whether the airline’s contract terms are ‘unfair’ if they put customers at an unfair disadvantage.
Under consumer law, businesses must show a total price that includes all unavoidable charges, rather than adding extra charges separately or later in the process, as this ensures consumers can effectively compare prices and understand the true cost of what they are buying.
“Lots of families save up to afford a summer holiday and we know that extra charges can quickly bump up the price,” commented Hayley Fletcher, who is the Senior Director of Consumer Protection at the CMA.
“Our investigation will consider Ryanair’s approach to family seat reservations and how the cost is presented to consumers to determine whether they comply with consumer law.
“For the past year, we’ve told businesses to ensure their customers are shown the total price upfront – those who don’t face the very real possibility of action from the CMA.”
At present, the CMA is currently at the beginning of its investigation, and has reached no conclusions about whether Ryanair has broken the law.
Morrisons has launched a nationwide search for its first Chief Doughnut Tester
Emily Sergeant
Today is National Doughnut Day, and to celebrate, Morrisons is on the look-out for one sweet treat fan to take on a new role.
That’s right – today (5 June) is National Doughnut Day, and Morrisons is officially on the hunt for the nation’s ultimate doughnut devotee with the launch of its brand-new (and delicious) role, The Chief Doughnut Tester – with all glaze enthusiasts, sprinkle connoisseurs, and jam-filled aficionados urged to get applying.
The search is on to crown one lucky fan who’ll take on the dream job of taste-testing their way through the supermarket‘s range of doughnuts.
The Chief Doughnut Tester is more than just a title, Morrisons says it’s ‘serious business’.
Morrisons has launched a nationwide search for its first-ever Chief Doughnut Tester / Credit: Morrisons
The new hire will be tasked with taste-testing doughnuts before they hit the shelves, giving verdicts on new flavours and textures, all in the name of research.
The role will also involve teaming up with Morrisons’ internal doughnut-expert team to develop new and limited-edition treats that’ll be in stores next year.
Crowned as the nation’s definitive doughnut authority, the selected winner won’t just earn the title of Chief Doughnut Tester, they’ll also receive the ultimate of sweet perks – a year’s free supply of Morrisons fresh doughnuts, which the retailer sells more than 1.1 million of weekly.
Fancy it then? Does this sound like you?
Aspiring Chief Doughnut Testers can apply on the Morrisons website here, by filling in a short 200-words about why’re the ideal candidate.
Applications close at midnight tonight (Friday 5 June), so you’ll need to be quick.
The Hoot -
27th July 2022 
